Biological Reconstructions

Our center excels in biological reconstruction techniques to restore bone and soft tissue defects following tumor resection. These methods leverage the body’s natural healing processes, offering durable and functional outcomes. Our approach ensures minimal complications and optimal integration with surrounding tissues, guided by strict oncological principles.

Autologous Bone Grafting Techniques

We utilize the patient’s own bone tissue for reconstruction, ensuring biocompatibility and reducing rejection risks:

• Vascularized Fibular Grafts: Harvesting fibular bone with its blood supply for robust reconstruction of long bone defects.
• Iliac Crest Bone Grafts: Using cancellous bone from the iliac crest for smaller defects, promoting rapid healing.
• Local Bone Grafting: Utilizing adjacent bone tissue for reconstruction, minimizing donor site morbidity.
• Bone Transport Techniques: Gradual distraction osteogenesis to regenerate bone in large segmental defects.

Allograft Reconstruction Techniques

We employ donor bone tissue for structural reconstruction, particularly for large defects:

• Structural Allografts: Using cortical bone allografts to restore skeletal integrity in major resections.
• Osteoarticular Allografts: Replacing entire joint surfaces with donor tissue for joint preservation.
• Intercalary Allografts: Bridging segmental bone defects while preserving native joints.
• Allograft-Prosthetic Composites: Combining allografts with prosthetic implants for enhanced stability and function.

Advanced Tissue Engineering

We integrate cutting-edge tissue engineering techniques to enhance biological reconstruction:

• Bone Morphogenetic Proteins (BMPs): Using growth factors to stimulate bone regeneration and healing.
• Scaffold-Based Reconstruction: Employing biocompatible scaffolds to support tissue regeneration in complex defects.
• Stem Cell Therapy: Incorporating mesenchymal stem cells to enhance bone and soft tissue regeneration.
• 3D-Printed Biological Constructs: Custom-designed scaffolds for precise reconstruction of complex anatomical structures.

Specialized Reconstruction Considerations

We tailor our approach to address challenging anatomical locations and patient-specific needs:

• Pediatric Reconstructions: Techniques preserving growth plates and ensuring long-term functionality in young patients.
• Pelvic Reconstructions: Complex allograft or vascularized grafts for pelvic bone defects post-tumor resection.
• Spinal Reconstructions: Using allografts or scaffolds to restore spinal stability and alignment.
• Soft Tissue Reconstruction: Combining biological grafts with flap techniques for optimal soft tissue coverage.

Our Comprehensive Approach

We employ a multidisciplinary team approach involving orthopaedic oncologists, radiologists, and tissue engineers to ensure optimal outcomes. Our services include:

• Pre-surgical imaging and planning for precise reconstruction
• Collaboration with tissue banks for high-quality allografts
• Use of advanced imaging (CT, MRI) for defect assessment
• Minimization of complications through meticulous surgical techniques
• Coordination with rehabilitation teams for post-surgical recovery
• Patient education on reconstruction procedures and long-term outcomes

Our dedication to biological reconstruction ensures patients regain functionality and quality of life. By leveraging natural tissue integration and advanced engineering, we provide durable, patient-centered solutions for complex bone and soft tissue defects.